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Immutep (ASX:IMM) - CEO, Marc Voigt
CEO, Marc Voigt
Source: Finance News Network
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  • Immutep (IMM) and its partner, EOC Pharma, confirmed they will continue advancing Efti for treating metastatic breast cancer
  • This follows EOC Pharma’s analysis of progression-free survival (PFS) data from Immutep’s recent clinical study on Efti
  • Results showed PFS data was in favour of Efti at the six month mark
  • EOC Pharma is Immutep’s exclusive licensee for Efti in China
  • Due to these findings, EOC will continue its Efti study in Shanghai and results will be reported later this year
  • Immutep is up a healthy 16.7 per cent and shares are trading for 14 cents each

Immutep (IMM) and its partner, EOC Pharma, have discussed the AIPAC results and confirmed they will continue advancing Efti for treating metastatic breast cancer.

The confirmation follows EOC Pharma’s analysis of the recently reported progression-free survival (PFS) data. This includes the analysis from Immutep’s phase IIb AIPAC study.

“We are very pleased about the discussions with EOC Pharma and their perspectives on Efti in metastatic breast cancer and we look forward to further developing our collaboration with them,” Immutep CEO Marc Voigt said.

EOC Pharma is an oncology pharmaceutical company based in Shanghai. It is Immutep’s exclusive licensee of Efti (Eftilagimod alpha) for the China market.

Under its agreement with Immutep, EOC Pharma will make future payments to Immutep if Efti achieves specific development milestones as well as royalties on sales. Terms also include EOC Pharma funding the Chinese development of the cancer-treating drug.

Immutep’s phase IIb AIPAC clinical trial was completed in March 2020. On the 26th, the company reported pleasing results.

The company treated 227 metastatic breast cancer patients with Efti and paclitaxel (Taxol-chemotherapy medication) to boost the T-cell immune response against tumours.

Reportedly, 63 per cent of the patients who received paclitaxel and Efti were progression-free at the end of six months. The overall response rate (ORR) increased to 48.3 per cent in the Efti group, up from 38.4 per cent.

Results also showed progression-free survival (PFS) was in favour of Efti over the placebo at the 6-month mark.

“Our analysis of the overall and subgroup data suggests there is a definite opportunity to progress Efti for Chinese patients with metastatic breast cancer,” EOC Pharma CEO Xiaoming Zou said.

“The data allows us to more specifically address certain meaningful patient populations and maximise the chance of a benefit for those patient groups,” he added.

EOC Pharma will continue its ongoing phase I EOC202A1101 study of Efti in metastatic breast cancer in China. The last patient was enrolled and safely dosed in February and data is expected to be reported later this year.

Immutep is up a healthy 16.7 per cent and shares are trading for 14 cents each at 12:48 pm AEST.

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